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Negative Regulation of the Tumor Suppressor p53 Gene by MicroRNAs
The tumor suppressor p53, encoded by the TP53 gene, is recognized as the guardian of the human genome because it regulates many downstream genes to exercise its function in cell cycle and cell death. Recent reports have revealed that several microRNAs (miRNAs) are important components of the p53 tum...
Autores principales: | Kumar, Munish, Lu, Zhongxin, Takwi, Apana Agha L., Chen, Weiqun, Callander, Natalie S., Ramos, Kenneth S., Young, Ken H., Li, Yong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021102/ https://www.ncbi.nlm.nih.gov/pubmed/20935678 http://dx.doi.org/10.1038/onc.2010.457 |
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