Rapamycin Blocks Production of KSHV/HHV8: Insights into the Anti-Tumor Activity of an Immunosuppressant Drug

BACKGROUND: Infection with Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8) often results in the development of fatal tumors in immunocompromised patients. Studies of renal transplant recipients show that use of the immunosuppressant drug rapamycin, an mTOR inhibitor, both prevents and can i...

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Detalles Bibliográficos
Autores principales: Nichols, Lisa A., Adang, Laura A., Kedes, Dean H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021514/
https://www.ncbi.nlm.nih.gov/pubmed/21264294
http://dx.doi.org/10.1371/journal.pone.0014535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021514/
https://www.ncbi.nlm.nih.gov/pubmed/21264294
http://dx.doi.org/10.1371/journal.pone.0014535

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