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The Menin Tumor Suppressor Protein Is Phosphorylated in Response to DNA Damage

BACKGROUND: Multiple endocrine neoplasia type 1 (MEN1) is a heritable cancer syndrome characterized by tumors of the pituitary, pancreas and parathyroid. Menin, the product of the MEN1 gene, is a tumor suppressor protein that functions in part through the regulation of transcription mediated by inte...

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Detalles Bibliográficos
Autores principales: Francis, Joshua, Lin, Wenchu, Rozenblatt-Rosen, Orit, Meyerson, Matthew
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021530/
https://www.ncbi.nlm.nih.gov/pubmed/21264250
http://dx.doi.org/10.1371/journal.pone.0016119