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Insulin Reduces Neuronal Excitability by Turning on GABA(A) Channels that Generate Tonic Current

Insulin signaling to the brain is important not only for metabolic homeostasis but also for higher brain functions such as cognition. GABA (γ-aminobutyric acid) decreases neuronal excitability by activating GABA(A) channels that generate phasic and tonic currents. The level of tonic inhibition in ne...

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Detalles Bibliográficos
Autores principales: Jin, Zhe, Jin, Yang, Kumar-Mendu, Suresh, Degerman, Eva, Groop, Leif, Birnir, Bryndis
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021545/
https://www.ncbi.nlm.nih.gov/pubmed/21264261
http://dx.doi.org/10.1371/journal.pone.0016188