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A Model for Transition of 5′-Nuclease Domain of DNA Polymerase I from Inert to Active Modes
Bacteria contain DNA polymerase I (PolI), a single polypeptide chain consisting of ∼930 residues, possessing DNA-dependent DNA polymerase, 3′-5′ proofreading and 5′-3′ exonuclease (also known as flap endonuclease) activities. PolI is particularly important in the processing of Okazaki fragments gene...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021548/ https://www.ncbi.nlm.nih.gov/pubmed/21264264 http://dx.doi.org/10.1371/journal.pone.0016213 |