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Formulation and Evaluation of Extended-Release Solid Dispersion of Metformin Hydrochloride
The purpose of this research was to formulate and characterize solid dispersion (SD) of metformin hydrochloride using methocel K100M as the carrier by the solvent evaporation and cogrinding method. The influence of drug polymer ratio on drug release was studied by dissolution tests. Characterization...
Autores principales: | Patil, SA, Kuchekar, BS, Chabukswar, AR, Jagdale, SC |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021685/ https://www.ncbi.nlm.nih.gov/pubmed/21264113 http://dx.doi.org/10.4103/0975-1483.63147 |
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