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Regulatory T cells can prevent memory CD8(+) T-cell-mediated rejection following polymorphonuclear cell depletion

Accumulating evidence suggests that alloreactive memory T cells (Tm) may form a barrier to tolerance induction in large animals and humans due in part to a resistance to suppression by Treg. However, why Tm are resistant to regulation and how the Tm response to an allograft differs from that of naïv...

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Detalles Bibliográficos
Autores principales:	Jones, Nick D, Brook, Matthew O, Carvalho-Gaspar, Manuela, Luo, Shiqao, Wood, Kathryn J
Formato:	Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2010
Materias:	Immunomodulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021718/ https://www.ncbi.nlm.nih.gov/pubmed/20865790 http://dx.doi.org/10.1002/eji.201040671

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