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Exploitation of Herpesviral Transactivation Allows Quantitative Reporter Gene-Based Assessment of Virus Entry and Neutralization

Herpesviral entry is a highly elaborated process requiring many proteins to act in precise conjunction. Neutralizing antibodies interfere with this process to abrogate viral infection. Based on promoter transactivation of a reporter gene we established a novel method to quantify herpesvirus entry an...

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Detalles Bibliográficos
Autores principales: Reinhard, Henrike, Le, Vu Thuy Khanh, Ohlin, Mats, Hengel, Hartmut, Trilling, Mirko
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022015/
https://www.ncbi.nlm.nih.gov/pubmed/21264213
http://dx.doi.org/10.1371/journal.pone.0014532

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