A Key Role for Poly(ADP-Ribose) Polymerase 3 in Ectodermal Specification and Neural Crest Development

BACKGROUND: The PARP family member poly(ADP-ribose) polymerase 3 (PARP3) is structurally related to the well characterized PARP1 that orchestrates cellular responses to DNA strand breaks and cell death by the synthesis of poly(ADP-ribose). In contrast to PARP1 and PARP2, the functions of PARP3 are u...

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Detalles Bibliográficos
Autores principales: Rouleau, Michèle, Saxena, Vishal, Rodrigue, Amélie, Paquet, Eric R., Gagnon, Abbie, Hendzel, Michael J., Masson, Jean-Yves, Ekker, Marc, Poirier, Guy G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022025/
https://www.ncbi.nlm.nih.gov/pubmed/21264220
http://dx.doi.org/10.1371/journal.pone.0015834

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