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A Humanin Derivative Reduces Amyloid Beta Accumulation and Ameliorates Memory Deficit in Triple Transgenic Mice
Humanin (HN), a 24-residue peptide, was identified as a novel neuroprotective factor and shows anti-cell death activity against a wide spectrum of Alzheimer's disease (AD)-related cytotoxicities, including exposure to amyloid beta (Abeta), in vitro. We previously demonstrated that the injection...
Autores principales: | Niikura, Takako, Sidahmed, Elkhansa, Hirata-Fukae, Chiho, Aisen, Paul S., Matsuoka, Yasuji |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022031/ https://www.ncbi.nlm.nih.gov/pubmed/21264226 http://dx.doi.org/10.1371/journal.pone.0016259 |
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