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Educational paper: Primary immunodeficiencies in children: a diagnostic challenge

Primary immunodeficiencies (PIDs) are characterized by an increased susceptibility to infections due to defects in one ore more components of the immune system. Although most PIDs are relatively rare, they are more frequent than generally acknowledged. Early diagnosis and treatment of PIDs save live...

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Detalles Bibliográficos
Autores principales: de Vries, Esther, Driessen, Gertjan
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022152/
https://www.ncbi.nlm.nih.gov/pubmed/21170549
http://dx.doi.org/10.1007/s00431-010-1358-5
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author de Vries, Esther
Driessen, Gertjan
author_facet de Vries, Esther
Driessen, Gertjan
author_sort de Vries, Esther
collection PubMed
description Primary immunodeficiencies (PIDs) are characterized by an increased susceptibility to infections due to defects in one ore more components of the immune system. Although most PIDs are relatively rare, they are more frequent than generally acknowledged. Early diagnosis and treatment of PIDs save lives, prevent morbidity, and improve quality of life. This early diagnosis is the task of the pediatrician who encounters the child for the first time: he/she should suspect potential PID in time and perform the appropriate diagnostic tests. In this educational paper, the first in a series of five, we will describe the most common clinical presentations of PIDs and offer guidelines for the diagnostic process, as well as a brief overview of therapeutic possibilities and prognosis.
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spelling pubmed-30221522011-02-22 Educational paper: Primary immunodeficiencies in children: a diagnostic challenge de Vries, Esther Driessen, Gertjan Eur J Pediatr Review Primary immunodeficiencies (PIDs) are characterized by an increased susceptibility to infections due to defects in one ore more components of the immune system. Although most PIDs are relatively rare, they are more frequent than generally acknowledged. Early diagnosis and treatment of PIDs save lives, prevent morbidity, and improve quality of life. This early diagnosis is the task of the pediatrician who encounters the child for the first time: he/she should suspect potential PID in time and perform the appropriate diagnostic tests. In this educational paper, the first in a series of five, we will describe the most common clinical presentations of PIDs and offer guidelines for the diagnostic process, as well as a brief overview of therapeutic possibilities and prognosis. Springer-Verlag 2010-12-18 2011 /pmc/articles/PMC3022152/ /pubmed/21170549 http://dx.doi.org/10.1007/s00431-010-1358-5 Text en © The Author(s) 2010 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Review
de Vries, Esther
Driessen, Gertjan
Educational paper: Primary immunodeficiencies in children: a diagnostic challenge
title Educational paper: Primary immunodeficiencies in children: a diagnostic challenge
title_full Educational paper: Primary immunodeficiencies in children: a diagnostic challenge
title_fullStr Educational paper: Primary immunodeficiencies in children: a diagnostic challenge
title_full_unstemmed Educational paper: Primary immunodeficiencies in children: a diagnostic challenge
title_short Educational paper: Primary immunodeficiencies in children: a diagnostic challenge
title_sort educational paper: primary immunodeficiencies in children: a diagnostic challenge
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022152/
https://www.ncbi.nlm.nih.gov/pubmed/21170549
http://dx.doi.org/10.1007/s00431-010-1358-5
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