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Metabolomic Profiling for Identification of Novel Potential Biomarkers in Cardiovascular Diseases

Metabolomics involves the identification and quantification of metabolites present in a biological system. Three different approaches can be used: metabolomic fingerprinting, metabolic profiling, and metabolic footprinting, in order to evaluate the clinical course of a disease, patient recovery, cha...

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Detalles Bibliográficos
Autores principales: Barderas, Maria G., Laborde, Carlos M., Posada, Maria, de la Cuesta, Fernando, Zubiri, Irene, Vivanco, Fernando, Alvarez-Llamas, Gloria
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022229/
https://www.ncbi.nlm.nih.gov/pubmed/21274272
http://dx.doi.org/10.1155/2011/790132
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author Barderas, Maria G.
Laborde, Carlos M.
Posada, Maria
de la Cuesta, Fernando
Zubiri, Irene
Vivanco, Fernando
Alvarez-Llamas, Gloria
author_facet Barderas, Maria G.
Laborde, Carlos M.
Posada, Maria
de la Cuesta, Fernando
Zubiri, Irene
Vivanco, Fernando
Alvarez-Llamas, Gloria
author_sort Barderas, Maria G.
collection PubMed
description Metabolomics involves the identification and quantification of metabolites present in a biological system. Three different approaches can be used: metabolomic fingerprinting, metabolic profiling, and metabolic footprinting, in order to evaluate the clinical course of a disease, patient recovery, changes in response to surgical intervention or pharmacological treatment, as well as other associated features. Characteristic patterns of metabolites can be revealed that broaden our understanding of a particular disorder. In the present paper, common strategies and analytical techniques used in metabolomic studies are reviewed, particularly with reference to the cardiovascular field.
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spelling pubmed-30222292011-01-27 Metabolomic Profiling for Identification of Novel Potential Biomarkers in Cardiovascular Diseases Barderas, Maria G. Laborde, Carlos M. Posada, Maria de la Cuesta, Fernando Zubiri, Irene Vivanco, Fernando Alvarez-Llamas, Gloria J Biomed Biotechnol Review Article Metabolomics involves the identification and quantification of metabolites present in a biological system. Three different approaches can be used: metabolomic fingerprinting, metabolic profiling, and metabolic footprinting, in order to evaluate the clinical course of a disease, patient recovery, changes in response to surgical intervention or pharmacological treatment, as well as other associated features. Characteristic patterns of metabolites can be revealed that broaden our understanding of a particular disorder. In the present paper, common strategies and analytical techniques used in metabolomic studies are reviewed, particularly with reference to the cardiovascular field. Hindawi Publishing Corporation 2011 2011-01-02 /pmc/articles/PMC3022229/ /pubmed/21274272 http://dx.doi.org/10.1155/2011/790132 Text en Copyright © 2011 Maria G. Barderas et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Barderas, Maria G.
Laborde, Carlos M.
Posada, Maria
de la Cuesta, Fernando
Zubiri, Irene
Vivanco, Fernando
Alvarez-Llamas, Gloria
Metabolomic Profiling for Identification of Novel Potential Biomarkers in Cardiovascular Diseases
title Metabolomic Profiling for Identification of Novel Potential Biomarkers in Cardiovascular Diseases
title_full Metabolomic Profiling for Identification of Novel Potential Biomarkers in Cardiovascular Diseases
title_fullStr Metabolomic Profiling for Identification of Novel Potential Biomarkers in Cardiovascular Diseases
title_full_unstemmed Metabolomic Profiling for Identification of Novel Potential Biomarkers in Cardiovascular Diseases
title_short Metabolomic Profiling for Identification of Novel Potential Biomarkers in Cardiovascular Diseases
title_sort metabolomic profiling for identification of novel potential biomarkers in cardiovascular diseases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022229/
https://www.ncbi.nlm.nih.gov/pubmed/21274272
http://dx.doi.org/10.1155/2011/790132
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