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Six Genes Associated with the Clinical Phenotypes of Individuals with Deficient and Proficient DNA Repair

Xeroderma pigmentosum (XP) is a genetic disorder characterised by hypo-/hyperpigmentation, increased sensitivity to ultraviolet (UV)-radiation and an up to 2000-fold increased skin cancer risk. Cells from XP-patients are defective in nucleotide excision repair (NER) responsible for repair of UV-indu...

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Detalles Bibliográficos
Autores principales:	Gremmel, Tobias, Wild, Susanne, Schuller, Winfried, Kürten, Viola, Dietz, Klaus, Krutmann, Jean, Berneburg, Mark
Formato:	Texto
Lenguaje:	English
Publicado:	Libertas Academica 2008
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022359/ https://www.ncbi.nlm.nih.gov/pubmed/21566739

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