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Synthetic Associations Are Unlikely to Account for Many Common Disease Genome-Wide Association Signals
Synthetic associations have been posited as a possible explanation for missing heritability in complex disease. We show several lines of evidence which suggest that, while possible, these synthetic associations are not common.
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022527/ https://www.ncbi.nlm.nih.gov/pubmed/21267062 http://dx.doi.org/10.1371/journal.pbio.1000580 |