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PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration
The normal function of poly (ADP-ribose) polymerase-1 (PARP-1) is the routine repair of DNA damage by adding poly (ADP ribose) polymers in response to a variety of cellular stresses. Recently, it has become widely appreciated that PARP-1 also participates in diverse physiological and pathological fu...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022541/ https://www.ncbi.nlm.nih.gov/pubmed/21176168 http://dx.doi.org/10.1186/1478-811X-8-31 |