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PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

The normal function of poly (ADP-ribose) polymerase-1 (PARP-1) is the routine repair of DNA damage by adding poly (ADP ribose) polymers in response to a variety of cellular stresses. Recently, it has become widely appreciated that PARP-1 also participates in diverse physiological and pathological fu...

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Detalles Bibliográficos
Autores principales: Chaitanya, Ganta Vijay, Alexander, Jonathan S, Babu, Phanithi Prakash
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022541/
https://www.ncbi.nlm.nih.gov/pubmed/21176168
http://dx.doi.org/10.1186/1478-811X-8-31