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Lack of the pattern recognition molecule mannose-binding lectin increases susceptibility to influenza A virus infection
BACKGROUND: Mannose-binding lectin (MBL), a pattern recognition innate immune molecule, inhibits influenza A virus infection in vitro. MBL deficiency due to gene polymorphism in humans has been associated with infection susceptibility. These clinical observations were confirmed by animal model studi...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022599/ https://www.ncbi.nlm.nih.gov/pubmed/21182784 http://dx.doi.org/10.1186/1471-2172-11-64 |