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Lack of the pattern recognition molecule mannose-binding lectin increases susceptibility to influenza A virus infection

BACKGROUND: Mannose-binding lectin (MBL), a pattern recognition innate immune molecule, inhibits influenza A virus infection in vitro. MBL deficiency due to gene polymorphism in humans has been associated with infection susceptibility. These clinical observations were confirmed by animal model studi...

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Detalles Bibliográficos
Autores principales:	Chang, Wei-Chuan, White, Mitchell R, Moyo, Patience, McClear, Sheree, Thiel, Steffen, Hartshorn, Kevan L, Takahashi, Kazue
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022599/ https://www.ncbi.nlm.nih.gov/pubmed/21182784 http://dx.doi.org/10.1186/1471-2172-11-64

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