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The modulation of TRPM7 currents by nafamostat mesilate depends directly upon extracellular concentrations of divalent cations

Concentrations of extracellular divalent cations (Ca(2+ )and Mg(2+)) fall substantially during intensive synaptic transmission as well as during some pathophysiological conditions such as epilepsy and brain ischemia. Here we report that a synthetic serine protease inhibitor, nafamostat mesylate (NM)...

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Detalles Bibliográficos
Autores principales:	Chen, Xuanmao, Numata, Tomohiro, Li, Minghua, Mori, Yasuo, Orser, Beverley A, Jackson, Michael F, Xiong, Zhi-Gang, MacDonald, John F
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022637/ https://www.ncbi.nlm.nih.gov/pubmed/21122141 http://dx.doi.org/10.1186/1756-6606-3-38

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