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Molecular cloning, characterization, genomic organization and promoter analysis of the α1,6-fucosyltransferase gene (fut8) expressed in the rat hybridoma cell line YB2/0

BACKGROUND: The rat hybridoma cell line YB2/0 appears a good candidate for the large-scale production of low fucose recombinant mAbs due to its lower expression of fut8 gene than other commonly used rodent cell lines. However, important variations of the fucose content of recombinant mAbs are observ...

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Detalles Bibliográficos
Autores principales:	Teylaert, Béatrice, Meurice, Edwige, Bobowski, Marie, Harduin-Lepers, Anne, Gaucher, Christine, Fontayne, Alexandre, Jorieux, Sylvie, Delannoy, Philippe
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022693/ https://www.ncbi.nlm.nih.gov/pubmed/21208406 http://dx.doi.org/10.1186/1472-6750-11-1

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