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HP1 Recruits Activity-Dependent Neuroprotective Protein to H3K9me3 Marked Pericentromeric Heterochromatin for Silencing of Major Satellite Repeats
H3 lysine 9 trimethylation (H3K9me3) is a histone posttranslational modification (PTM) that has emerged as hallmark of pericentromeric heterochromatin. This constitutive chromatin domain is composed of repetitive DNA elements, whose transcription is differentially regulated. Mammalian cells contain...
Autores principales: | Mosch, Kerstin, Franz, Henriette, Soeroes, Szabolcs, Singh, Prim B., Fischle, Wolfgang |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022755/ https://www.ncbi.nlm.nih.gov/pubmed/21267468 http://dx.doi.org/10.1371/journal.pone.0015894 |
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