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The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNA
BACKGROUND: Discovery that the transcriptional output of the human genome is far more complex than predicted by the current set of protein-coding annotations and that most RNAs produced do not appear to encode proteins has transformed our understanding of genome complexity and suggests new paradigms...
Autores principales: | Kapranov, Philipp, St Laurent, Georges, Raz, Tal, Ozsolak, Fatih, Reynolds, C Patrick, Sorensen, Poul HB, Reaman, Gregory, Milos, Patrice, Arceci, Robert J, Thompson, John F, Triche, Timothy J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022773/ https://www.ncbi.nlm.nih.gov/pubmed/21176148 http://dx.doi.org/10.1186/1741-7007-8-149 |
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