Induction of HSPA4 and HSPA14 by NBS1 overexpression contributes to NBS1-induced in vitro metastatic and transformation activity

BACKGROUND: Nijmegen breakage syndrome (NBS) is a chromosomal-instability syndrome associated with cancer predisposition, radiosensitivity, microcephaly, and growth retardation. The NBS gene product, NBS1 (p95) or nibrin, is a part of the MRN complex, a central player associated with double-strand b...

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Detalles Bibliográficos
Autores principales: Wu, Chung-Yin, Lin, Chih-Ta, Wu, Min-Zu, Wu, Kou-Juey
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022804/
https://www.ncbi.nlm.nih.gov/pubmed/21208456
http://dx.doi.org/10.1186/1423-0127-18-1

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