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Strand-specific PCR of UV radiation-damaged genomic DNA revealed an essential role of DNA-PKcs in the transcription-coupled repair

BACKGROUND: In eukaryotic cells, there are two sub-pathways of nucleotide excision repair (NER), the global genome (gg) NER and the transcription-coupled repair (TCR). TCR can preferentially remove the bulky DNA lesions located at the transcribed strand of a transcriptional active gene more rapidly...

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Detalles Bibliográficos
Autores principales:	An, Jing, Yang, Tianyi, Huang, Yuecheng, Liu, Feng, Sun, Jingfen, Wang, Yu, Xu, Qingzhi, Wu, Dechang, Zhou, Pingkun
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022811/ https://www.ncbi.nlm.nih.gov/pubmed/21214942 http://dx.doi.org/10.1186/1471-2091-12-2

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