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Glycogen synthase kinase-3β inactivation inhibits tumor necrosis factor-α production in microglia by modulating nuclear factor κB and MLK3/JNK signaling cascades

BACKGROUND: Deciphering the mechanisms that modulate the inflammatory response induced by microglial activation not only improves our insight into neuroinflammation but also provides avenues for designing novel therapies that could halt inflammation-induced neuronal degeneration. Decreasing glycogen...

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Detalles Bibliográficos
Autores principales:	Wang, Mei-Jen, Huang, Hsin-Yi, Chen, Wu-Fu, Chang, Hui-Fen, Kuo, Jon-Son
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022821/ https://www.ncbi.nlm.nih.gov/pubmed/21194439 http://dx.doi.org/10.1186/1742-2094-7-99

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