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Hydrogen peroxide induced genomic instability in nucleotide excision repair-deficient lymphoblastoid cells

BACKGROUND: The Nucleotide Excision Repair (NER) pathway specialises in UV-induced DNA damage repair. Inherited defects in the NER can predispose individuals to Xeroderma Pigmentosum (XP). UV-induced DNA damage cannot account for the manifestation of XP in organ systems not directly exposed to sunli...

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Detalles Bibliográficos
Autores principales:	Gopalakrishnan, Kalpana, Low, Grace Kah Mun, Ting, Aloysius Poh Leong, Srikanth, Prarthana, Slijepcevic, Predrag, Hande, M Prakash
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022891/ https://www.ncbi.nlm.nih.gov/pubmed/21176161 http://dx.doi.org/10.1186/2041-9414-1-16

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