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Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications
Recent evidence indicates that leptin regulates appetite and energy expenditure, at least in part by inhibiting serotonin synthesis and release from brainstem neurons. To demonstrate that this pathway works postnatally, we used a conditional, brainstem-specific mouse CreER(T2) driver to show that le...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023132/ https://www.ncbi.nlm.nih.gov/pubmed/21187319 http://dx.doi.org/10.1084/jem.20101940 |