Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications

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Recent evidence indicates that leptin regulates appetite and energy expenditure, at least in part by inhibiting serotonin synthesis and release from brainstem neurons. To demonstrate that this pathway works postnatally, we used a conditional, brainstem-specific mouse CreER(T2) driver to show that le...

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Detalles Bibliográficos
Autores principales: Yadav, Vijay K., Oury, Franck, Tanaka, Kenji, Thomas, Tiffany, Wang, Ying, Cremers, Serge, Hen, Rene, Krust, Andree, Chambon, Pierre, Karsenty, Gerard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023132/
https://www.ncbi.nlm.nih.gov/pubmed/21187319
http://dx.doi.org/10.1084/jem.20101940
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