Local microbleeding facilitates IL-6– and IL-17–dependent arthritis in the absence of tissue antigen recognition by activated T cells

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Cognate antigen recognition by CD4(+) T cells is thought to contribute to the tissue specificity of various autoimmune diseases, particularly those associated with class II MHC alleles. However, we show that localized class II MHC–dependent arthritis in F759 mice depends on local events that result...

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Detalles Bibliográficos
Autores principales: Murakami, Masaaki, Okuyama, Yuko, Ogura, Hideki, Asano, Shogo, Arima, Yasunobu, Tsuruoka, Mineko, Harada, Masaya, Kanamoto, Minoru, Sawa, Yukihisa, Iwakura, Yoichiro, Takatsu, Kiyoshi, Kamimura, Daisuke, Hirano, Toshio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023133/
https://www.ncbi.nlm.nih.gov/pubmed/21220456
http://dx.doi.org/10.1084/jem.20100900

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