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Local microbleeding facilitates IL-6– and IL-17–dependent arthritis in the absence of tissue antigen recognition by activated T cells
Cognate antigen recognition by CD4(+) T cells is thought to contribute to the tissue specificity of various autoimmune diseases, particularly those associated with class II MHC alleles. However, we show that localized class II MHC–dependent arthritis in F759 mice depends on local events that result...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023133/ https://www.ncbi.nlm.nih.gov/pubmed/21220456 http://dx.doi.org/10.1084/jem.20100900 |
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por Murakami, Masaaki, Okuyama, Yuko, Ogura, Hideki, Asano, Shogo, Arima, Yasunobu, Tsuruoka, Mineko, Harada, Masaya, Kanamoto, Minoru, Sawa, Yukihisa, Iwakura, Yoichiro, Takatsu, Kiyoshi, Kamimura, Daisuke, Hirano, Toshio
Publicado 2012
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Publicado 2012
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Online
Artículo
Texto