Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

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The 2009 pandemic H1N1 influenza pandemic demonstrated the global health threat of reassortant influenza strains. Herein, we report a detailed analysis of plasmablast and monoclonal antibody responses induced by pandemic H1N1 infection in humans. Unlike antibodies elicited by annual influenza vaccin...

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Detalles Bibliográficos
Autores principales: Wrammert, Jens, Koutsonanos, Dimitrios, Li, Gui-Mei, Edupuganti, Srilatha, Sui, Jianhua, Morrissey, Michael, McCausland, Megan, Skountzou, Ioanna, Hornig, Mady, Lipkin, W. Ian, Mehta, Aneesh, Razavi, Behzad, Del Rio, Carlos, Zheng, Nai-Ying, Lee, Jane-Hwei, Huang, Min, Ali, Zahida, Kaur, Kaval, Andrews, Sarah, Amara, Rama Rao, Wang, Youliang, Das, Suman Ranjan, O'Donnell, Christopher David, Yewdell, Jon W., Subbarao, Kanta, Marasco, Wayne A., Mulligan, Mark J., Compans, Richard, Ahmed, Rafi, Wilson, Patrick C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023136/
https://www.ncbi.nlm.nih.gov/pubmed/21220454
http://dx.doi.org/10.1084/jem.20101352
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