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Characterization of the Elongation Complex of Dengue Virus RNA Polymerase: ASSEMBLY, KINETICS OF NUCLEOTIDE INCORPORATION, AND FIDELITY

Dengue virus (DENV) infects 50–100 million people worldwide per year, causing severe public health problems. DENV RNA-dependent RNA polymerase, an attractive target for drug development, catalyzes de novo replication of the viral genome in three phases: initiation, transition, and elongation. The ai...

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Detalles Bibliográficos
Autores principales:	Jin, Zhinan, Deval, Jerome, Johnson, Kenneth A., Swinney, David C.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2011
Materias:	Enzymology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023504/ https://www.ncbi.nlm.nih.gov/pubmed/21078673 http://dx.doi.org/10.1074/jbc.M110.162685

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