Hepatitis C virus genotype 3a with phylogenetically distinct origin is circulating in Pakistan

BACKGROUND: Hepatitis C virus (HCV) is one of the leading causes of viral hepatitis worldwide and its genotype 3a is predominant in vast areas of Pakistan. FINDINGS: The present study reports the first full sequence of HCV 3a isolate PK-1 from Pakistan. This nucleotide sequence was compared with six...

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Autores principales: Rehman, Irshad-ur, Idrees, Muhammad, Ali, Muhammad, Ali, Liaqat, Butt, Sadia, Hussain, Abrar, Akbar, Haji, Afzal, Samia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023652/
https://www.ncbi.nlm.nih.gov/pubmed/21211024
http://dx.doi.org/10.1186/1479-0556-9-2
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author Rehman, Irshad-ur
Idrees, Muhammad
Ali, Muhammad
Ali, Liaqat
Butt, Sadia
Hussain, Abrar
Akbar, Haji
Afzal, Samia
author_facet Rehman, Irshad-ur
Idrees, Muhammad
Ali, Muhammad
Ali, Liaqat
Butt, Sadia
Hussain, Abrar
Akbar, Haji
Afzal, Samia
author_sort Rehman, Irshad-ur
collection PubMed
description BACKGROUND: Hepatitis C virus (HCV) is one of the leading causes of viral hepatitis worldwide and its genotype 3a is predominant in vast areas of Pakistan. FINDINGS: The present study reports the first full sequence of HCV 3a isolate PK-1 from Pakistan. This nucleotide sequence was compared with six other HCV genotype 3a full length sequences from different regions of the world by using statistical methods of phylogenetic analysis. CONCLUSION: The nucleotide difference of these seven sequences shows that HCV genotype 3a of phylogenetically distinct origin is circulating in Pakistan.
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spelling pubmed-30236522011-01-20 Hepatitis C virus genotype 3a with phylogenetically distinct origin is circulating in Pakistan Rehman, Irshad-ur Idrees, Muhammad Ali, Muhammad Ali, Liaqat Butt, Sadia Hussain, Abrar Akbar, Haji Afzal, Samia Genet Vaccines Ther Short Report BACKGROUND: Hepatitis C virus (HCV) is one of the leading causes of viral hepatitis worldwide and its genotype 3a is predominant in vast areas of Pakistan. FINDINGS: The present study reports the first full sequence of HCV 3a isolate PK-1 from Pakistan. This nucleotide sequence was compared with six other HCV genotype 3a full length sequences from different regions of the world by using statistical methods of phylogenetic analysis. CONCLUSION: The nucleotide difference of these seven sequences shows that HCV genotype 3a of phylogenetically distinct origin is circulating in Pakistan. BioMed Central 2011-01-06 /pmc/articles/PMC3023652/ /pubmed/21211024 http://dx.doi.org/10.1186/1479-0556-9-2 Text en Copyright ©2011 Rehman et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (<url>http://creativecommons.org/licenses/by/2.0</url>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Report
Rehman, Irshad-ur
Idrees, Muhammad
Ali, Muhammad
Ali, Liaqat
Butt, Sadia
Hussain, Abrar
Akbar, Haji
Afzal, Samia
Hepatitis C virus genotype 3a with phylogenetically distinct origin is circulating in Pakistan
title Hepatitis C virus genotype 3a with phylogenetically distinct origin is circulating in Pakistan
title_full Hepatitis C virus genotype 3a with phylogenetically distinct origin is circulating in Pakistan
title_fullStr Hepatitis C virus genotype 3a with phylogenetically distinct origin is circulating in Pakistan
title_full_unstemmed Hepatitis C virus genotype 3a with phylogenetically distinct origin is circulating in Pakistan
title_short Hepatitis C virus genotype 3a with phylogenetically distinct origin is circulating in Pakistan
title_sort hepatitis c virus genotype 3a with phylogenetically distinct origin is circulating in pakistan
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023652/
https://www.ncbi.nlm.nih.gov/pubmed/21211024
http://dx.doi.org/10.1186/1479-0556-9-2
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