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Improving the iMM904 S. cerevisiae metabolic model using essentiality and synthetic lethality data

BACKGROUND: Saccharomyces cerevisiae is the first eukaryotic organism for which a multi-compartment genome-scale metabolic model was constructed. Since then a sequence of improved metabolic reconstructions for yeast has been introduced. These metabolic models have been extensively used to elucidate...

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Detalles Bibliográficos
Autores principales: Zomorrodi, Ali R, Maranas, Costas D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023687/
https://www.ncbi.nlm.nih.gov/pubmed/21190580
http://dx.doi.org/10.1186/1752-0509-4-178

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