Cargando…

The Sodium Iodide Symporter (NIS) and Potential Regulators in Normal, Benign and Malignant Human Breast Tissue

INTRODUCTION: The presence, relevance and regulation of the Sodium Iodide Symporter (NIS) in human mammary tissue remains poorly understood. This study aimed to quantify relative expression of NIS and putative regulators in human breast tissue, with relationships observed further investigated in vit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ryan, James, Curran, Catherine E., Hennessy, Emer, Newell, John, Morris, John C., Kerin, Michael J., Dwyer, Roisin M.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023714/ https://www.ncbi.nlm.nih.gov/pubmed/21283523 http://dx.doi.org/10.1371/journal.pone.0016023

Ejemplares similares

Sodium iodide symporter (NIS) in extrathyroidal malignancies: focus on breast and urological cancer
por: Micali, Salvatore, et al.
Publicado: (2014)

The Sodium Iodide Symporter (NIS) as an Imaging Reporter for Gene, Viral, and Cell-based Therapies
por: Penheiter, Alan R, et al.
Publicado: (2012)

Glycosylation of Sodium/Iodide Symporter (NIS) Regulates Its Membrane Translocation and Radioiodine Uptake
por: Chung, Taemoon, et al.
Publicado: (2015)

Selective sodium iodide symporter (NIS) genetherapy of glioblastoma mediatedby EGFR-targeted lipopolyplexes
por: Spellerberg, Rebekka, et al.
Publicado: (2021)

A Probasin Promoter, Conditionally Replicating Adenovirus that Expresses the Sodium Iodide Symporter (NIS) for Radiovirotherapy of Prostate Cancer
por: Trujillo, Miguel A., et al.
Publicado: (2010)

A Steep Radioiodine Dose Response Scalable to Humans in Sodium Iodide Symporter (NIS) Mediated Radiovirotherapy for Prostate Cancer
por: Trujillo, Miguel A., et al.
Publicado: (2012)

Induction of Sodium/Iodide Symporter (NIS) Expression and Radioiodine Uptake in Non-Thyroid Cancer Cells
por: Liu, Zhi, et al.
Publicado: (2012)

Effect of thyroid statuses on sodium/iodide symporter (NIS) gene expression in the extrathyroidal tissues in mice
por: Harun-Or-Rashid, et al.
Publicado: (2010)

The G395R Mutation of the Sodium/Iodide Symporter (NIS) Gene in Patients with Dyshormonogenetic Congenital Hypothyroidism
por: Mostofizade, Neda, et al.
Publicado: (2013)

Imaging and targeted therapy of pancreatic ductal adenocarcinoma using the theranostic sodium iodide symporter (NIS) gene
por: Schmohl, Kathrin A., et al.
Publicado: (2017)

Inter-species variation in monovalent anion substrate selectivity and inhibitor sensitivity in the sodium iodide symporter (NIS)
por: Concilio, Susanna C., et al.
Publicado: (2020)

Dimerization of the Sodium/Iodide Symporter
por: Thompson, Rebecca J., et al.
Publicado: (2019)

Evolution and developmental expression of the sodium–iodide symporter ( NIS , slc5a5) gene family: Implications for perchlorate toxicology
por: Petersen, Ann M., et al.
Publicado: (2022)

The sodium/iodide symporter NIS is a transcriptional target of the p53-family members in liver cancer cells
por: Guerrieri, F, et al.
Publicado: (2013)

Codon-optimized Human Sodium Iodide Symporter (opt-hNIS) as a Sensitive Reporter and Efficient Therapeutic Gene
por: Kim, Young-Hwa, et al.
Publicado: (2015)

The sodium iodide symporter (NIS) as theranostic gene: its emerging role in new imaging modalities and non-viral gene therapy
por: Kitzberger, Carolin, et al.
Publicado: (2022)

Transcription Factor CREB3L1 Regulates the Expression of the Sodium/Iodide Symporter (NIS) in Rat Thyroid Follicular Cells
por: Di Giusto, Pablo, et al.
Publicado: (2022)

Taking Advantage of the TGFB1 Biology in Differentiated Thyroid Cancer to Stimulate Sodium Iodide Symporter (NIS)-Mediated Iodide Uptake in Engineered Mesenchymal Stem Cells
por: Han, Yang, et al.
Publicado: (2021)

High-throughput screening and chemotype-enrichment analysis of ToxCast phase II chemicals evaluated for human sodium-iodide symporter (NIS) inhibition
por: Wang, Jun, et al.
Publicado: (2019)

Molecular mechanisms of radioactive iodine refractoriness in differentiated thyroid cancer: Impaired sodium iodide symporter (NIS) expression owing to altered signaling pathway activity and intracellular localization of NIS
por: Oh, Ji Min, et al.
Publicado: (2021)

HSV-NIS, an oncolytic herpes simplex virus type 1 encoding human sodium iodide symporter for preclinical prostate cancer radiovirotherapy
por: Li, H, et al.
Publicado: (2013)

Sodium iodide symporter-targeted gene therapy in glioblastoma
por: Nicola, Juan Pablo, et al.
Publicado: (2023)

OR14-05 Taking Advantage Of The Interleukin-6-Biology In Differentiated Thyroid Cancer To Stimulate Sodium Iodide Symporter (NIS)-mediated Iodide Uptake In Engineered Mesenchymal Stem Cells
por: Florentine Koehler, Viktoria, et al.
Publicado: (2023)

An extremely high dietary iodide supply forestalls severe hypothyroidism in Na(+)/I(−) symporter (NIS) knockout mice
por: Ferrandino, Giuseppe, et al.
Publicado: (2017)

Tumor microenvironment affects exogenous sodium/iodide symporter expression
por: Castillo-Rivera, Fabio, et al.
Publicado: (2020)

Fluoride Exposure Induces Inhibition of Sodium/Iodide Symporter (NIS) Contributing to Impaired Iodine Absorption and Iodine Deficiency: Molecular Mechanisms of Inhibition and Implications for Public Health
por: Waugh, Declan Timothy
Publicado: (2019)

Decreased Expression of Thyroglobulin and Sodium Iodide Symporter Genes in Hashimoto's Thyroiditis
por: Popławska-Kita, Anna, et al.
Publicado: (2014)

Physiological sodium concentrations enhance the iodide affinity of the Na(+)/I(−) symporter
por: Nicola, Juan P., et al.
Publicado: (2014)

Palmitic Acid Downregulates Thyroglobulin (Tg), Sodium Iodide Symporter (NIS), and Thyroperoxidase (TPO) in Human Primary Thyrocytes: A Potential Mechanism by Which Lipotoxicity Affects Thyroid?
por: Zhao, Meng, et al.
Publicado: (2018)

Overexpression of Both Human Sodium Iodide Symporter (NIS) and BRG1-Bromodomain Synergistically Enhances Radioiodine Sensitivity by Stabilizing p53 through NPM1 Expression
por: Na, Juri, et al.
Publicado: (2023)

Sodium Iodide Symporter PET and BLI Noninvasively Reveal Mesoangioblast Survival in Dystrophic Mice
por: Holvoet, Bryan, et al.
Publicado: (2015)

In Vivo Myoblasts Tracking Using the Sodium Iodide Symporter Gene Expression in Dogs
por: Punzón, Isabel, et al.
Publicado: (2020)

Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter
por: Read, Martin L., et al.
Publicado: (2022)

Conserved charged amino acid residues in the extracellular region of sodium/iodide symporter are critical for iodide transport activity
por: Li, Chia-Cheng, et al.
Publicado: (2010)

MON-512 The Anti-Cancer Agent, Homoharringtonine, Induces the Sodium Iodide Symporter (NIS) Gene Expression in Culture Cells from Papillary Thyroid Cancer, as Well as Non-Thyroid Cancers
por: Kato, Kanako
Publicado: (2020)

Resveratrol Inhibits Sodium/Iodide Symporter Gene Expression and Function in Rat Thyroid Cells
por: Giuliani, Cesidio, et al.
Publicado: (2014)

Mechanisms of Sodium/Iodide Symporter-Mediated Mammary Gland Iodine Compensation during Lactation
por: Fu, Min, et al.
Publicado: (2022)

The glial fibrillary acidic protein promoter directs sodium/iodide symporter gene expression for radioiodine therapy of malignant glioma
por: LI, WEI, et al.
Publicado: (2013)

Enhanced anti-tumor effects of combined MDR1 RNA interference and human sodium/iodide symporter (NIS) radioiodine gene therapy using an adenoviral system in a colon cancer model
por: Ahn, S J, et al.
Publicado: (2010)

Redox Homeostasis in Thyroid Cancer: Implications in Na(+)/I(−) Symporter (NIS) Regulation
por: Cazarin, Juliana, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_q6e860ls4nlsq9bap43bvfemii