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Bayesian estimation of genomic copy number with single nucleotide polymorphism genotyping arrays
BACKGROUND: The identification of copy number aberration in the human genome is an important area in cancer research. We develop a model for determining genomic copy numbers using high-density single nucleotide polymorphism genotyping microarrays. The method is based on a Bayesian spatial normal mix...
Autores principales: | Guo, Beibei, Villagran, Alejandro, Vannucci, Marina, Wang, Jian, Davis, Caleb, Man, Tsz-Kwong, Lau, Ching, Guerra, Rudy |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023756/ https://www.ncbi.nlm.nih.gov/pubmed/21192799 http://dx.doi.org/10.1186/1756-0500-3-350 |
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