The Dynamic Processing of CD46 Intracellular Domains Provides a Molecular Rheostat for T Cell Activation

BACKGROUND: Adequate termination of an immune response is as important as the induction of an appropriate response. CD46, a regulator of complement activity, promotes T cell activation and differentiation towards a regulatory Tr1 phenotype. This Tr1 differentiation pathway is defective in patients w...

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Detalles Bibliográficos
Autores principales: Ni Choileain, Siobhan, Weyand, Nathan J., Neumann, Christian, Thomas, Joelle, So, Magdalene, Astier, Anne L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023775/
https://www.ncbi.nlm.nih.gov/pubmed/21283821
http://dx.doi.org/10.1371/journal.pone.0016287

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