Accounting for multiple comparisons in a genome-wide association study (GWAS)

BACKGROUND: As we enter an era when testing millions of SNPs in a single gene association study will become the standard, consideration of multiple comparisons is an essential part of determining statistical significance. Bonferroni adjustments can be made but are conservative due to the preponderan...

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Detalles Bibliográficos
Autores principales: Johnson, Randall C, Nelson, George W, Troyer, Jennifer L, Lautenberger, James A, Kessing, Bailey D, Winkler, Cheryl A, O'Brien, Stephen J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023815/
https://www.ncbi.nlm.nih.gov/pubmed/21176216
http://dx.doi.org/10.1186/1471-2164-11-724

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