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The Use of Antidepressant Drugs and the Lifetime Prevalence of Major Depressive Disorders in Italy
BACKGROUND: The increased use of antidepressant drugs (ADs) improved the response to the needs of care although some community surveys have shown that subjects without lifetime psychiatric diagnosis (anxiety/depression) used ADs. OBJECTIVES: To evaluate the appropriateness and amount of prescription...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Bentham Open
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023943/ https://www.ncbi.nlm.nih.gov/pubmed/21253459 http://dx.doi.org/10.2174/1745017901006010094 |
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author | Carta, Mauro Giovanni Aguglia, Eugenio Bocchetta, Alberto Balestrieri, Matteo Caraci, Filippo Casacchia, Massimo Dell’Osso, Liliana Sciascio, Guido Di Drago, Filippo Faravelli, Carlo Lecca, Maria Efisia Moro, Maria Francesca Morosini, Pier Luigi Nardini, Marcello Palumbo, Gabriella Hardoy, Maria Carolina |
author_facet | Carta, Mauro Giovanni Aguglia, Eugenio Bocchetta, Alberto Balestrieri, Matteo Caraci, Filippo Casacchia, Massimo Dell’Osso, Liliana Sciascio, Guido Di Drago, Filippo Faravelli, Carlo Lecca, Maria Efisia Moro, Maria Francesca Morosini, Pier Luigi Nardini, Marcello Palumbo, Gabriella Hardoy, Maria Carolina |
author_sort | Carta, Mauro Giovanni |
collection | PubMed |
description | BACKGROUND: The increased use of antidepressant drugs (ADs) improved the response to the needs of care although some community surveys have shown that subjects without lifetime psychiatric diagnosis (anxiety/depression) used ADs. OBJECTIVES: To evaluate the appropriateness and amount of prescription of psychotropic drugs in people with lifetime diagnosis of Major Depressive Disorder (MDD) by means of community survey with a semi-structured interview as a diagnostic instrument, administered by clinicians. METHODS: Study design: community survey. Study population: samples randomly drawn, after stratification from the adult population of municipal records. Sample size: 4.999 people were drawn in 7 centres of 6 Italian regions. TOOLS: questionnaire on psychotropic drug consumption, prescription, health services utilization; Structured Clinical Interview for DSM-IV modified (ANTAS); Training: interviewers were trained psychologists or medical doctors. RESULTS: 3.398 subjects were interviewed (68% of the recruited sample). The lifetime prevalence of DSM-IV MDD was 4.3% in males and 11.5% in females; antidepressant drugs were taken by 4.7% of subjects, 2.9% male and 5.9% female. 38% of males and 57% of females with lifetime diagnosis of MDD were taking ADs. CONCLUSIONS: Compared with studies using lay interviewers and structured tools the prevalence of the MDD was quite lower; ADs use was higher and tallied well with the data regarding antidepressant sales in Italy; the correspondence between lifetime diagnosis of MDD and ADs use was closer. |
format | Text |
id | pubmed-3023943 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Bentham Open |
record_format | MEDLINE/PubMed |
spelling | pubmed-30239432011-01-20 The Use of Antidepressant Drugs and the Lifetime Prevalence of Major Depressive Disorders in Italy Carta, Mauro Giovanni Aguglia, Eugenio Bocchetta, Alberto Balestrieri, Matteo Caraci, Filippo Casacchia, Massimo Dell’Osso, Liliana Sciascio, Guido Di Drago, Filippo Faravelli, Carlo Lecca, Maria Efisia Moro, Maria Francesca Morosini, Pier Luigi Nardini, Marcello Palumbo, Gabriella Hardoy, Maria Carolina Clin Pract Epidemiol Ment Health Article BACKGROUND: The increased use of antidepressant drugs (ADs) improved the response to the needs of care although some community surveys have shown that subjects without lifetime psychiatric diagnosis (anxiety/depression) used ADs. OBJECTIVES: To evaluate the appropriateness and amount of prescription of psychotropic drugs in people with lifetime diagnosis of Major Depressive Disorder (MDD) by means of community survey with a semi-structured interview as a diagnostic instrument, administered by clinicians. METHODS: Study design: community survey. Study population: samples randomly drawn, after stratification from the adult population of municipal records. Sample size: 4.999 people were drawn in 7 centres of 6 Italian regions. TOOLS: questionnaire on psychotropic drug consumption, prescription, health services utilization; Structured Clinical Interview for DSM-IV modified (ANTAS); Training: interviewers were trained psychologists or medical doctors. RESULTS: 3.398 subjects were interviewed (68% of the recruited sample). The lifetime prevalence of DSM-IV MDD was 4.3% in males and 11.5% in females; antidepressant drugs were taken by 4.7% of subjects, 2.9% male and 5.9% female. 38% of males and 57% of females with lifetime diagnosis of MDD were taking ADs. CONCLUSIONS: Compared with studies using lay interviewers and structured tools the prevalence of the MDD was quite lower; ADs use was higher and tallied well with the data regarding antidepressant sales in Italy; the correspondence between lifetime diagnosis of MDD and ADs use was closer. Bentham Open 2010-08-27 /pmc/articles/PMC3023943/ /pubmed/21253459 http://dx.doi.org/10.2174/1745017901006010094 Text en © Carta et al.; Licensee Bentham Open. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited. |
spellingShingle | Article Carta, Mauro Giovanni Aguglia, Eugenio Bocchetta, Alberto Balestrieri, Matteo Caraci, Filippo Casacchia, Massimo Dell’Osso, Liliana Sciascio, Guido Di Drago, Filippo Faravelli, Carlo Lecca, Maria Efisia Moro, Maria Francesca Morosini, Pier Luigi Nardini, Marcello Palumbo, Gabriella Hardoy, Maria Carolina The Use of Antidepressant Drugs and the Lifetime Prevalence of Major Depressive Disorders in Italy |
title | The Use of Antidepressant Drugs and the Lifetime Prevalence of Major Depressive Disorders in Italy |
title_full | The Use of Antidepressant Drugs and the Lifetime Prevalence of Major Depressive Disorders in Italy |
title_fullStr | The Use of Antidepressant Drugs and the Lifetime Prevalence of Major Depressive Disorders in Italy |
title_full_unstemmed | The Use of Antidepressant Drugs and the Lifetime Prevalence of Major Depressive Disorders in Italy |
title_short | The Use of Antidepressant Drugs and the Lifetime Prevalence of Major Depressive Disorders in Italy |
title_sort | use of antidepressant drugs and the lifetime prevalence of major depressive disorders in italy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023943/ https://www.ncbi.nlm.nih.gov/pubmed/21253459 http://dx.doi.org/10.2174/1745017901006010094 |
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