Characterization of the insulin sensitivity of ghrelin receptor KO mice using glycemic clamps

BACKGROUND: We and others have demonstrated previously that ghrelin receptor (GhrR) knock out (KO) mice fed a high fat diet (HFD) have increased insulin sensitivity and metabolic flexibility relative to WT littermates. A striking feature of the HFD-fed GhrR KO mouse is the dramatic decrease in hepat...

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Detalles Bibliográficos
Autores principales: Qi, Yong, Longo, Kenneth A, Giuliana, Derek J, Gagne, Samantha, McDonagh, Tom, Govek, Elizabeth, Nolan, Anna, Zou, Chaoseng, Morgan, Kristen, Hixon, Jeffrey, Saunders, Jeffrey O, DiStefano, Peter S, Geddes, Brad J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024223/
https://www.ncbi.nlm.nih.gov/pubmed/21211044
http://dx.doi.org/10.1186/1472-6793-11-1

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