Cargando…

Inhibition of telomerase activity by HDV ribozyme in cancers

BACKGROUND: Telomerase plays an important role in cell proliferation and carcinogenesis and is believed to be a good target for anti-cancer drugs. Elimination of template function of telomerase RNA may repress the telomerase activity. METHODS: A pseudo-knotted HDV ribozyme (g.RZ57) directed against...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Yingying, Gu, Junchao, Jin, Dachuan, Gao, Yanjing, Yuan, Mengbiao
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024244/ https://www.ncbi.nlm.nih.gov/pubmed/21208462 http://dx.doi.org/10.1186/1756-9966-30-1

Ejemplares similares

Topological constraints of structural elements in regulation of catalytic activity in HDV-like self-cleaving ribozymes
por: Webb, Chiu-Ho T., et al.
Publicado: (2016)

New tools provide a second look at HDV ribozyme structure, dynamics and cleavage
por: Kapral, Gary J., et al.
Publicado: (2014)

Inhibition of HIV-1 expression and replication by SOFA-HDV ribozymes against Tat and Rev mRNA sequences
por: Lainé, Sébastien, et al.
Publicado: (2009)

Disparate HDV ribozyme crystal structures represent intermediates on a rugged free-energy landscape
por: Sripathi, Kamali N., et al.
Publicado: (2014)

Characterization of the Trans Watson-Crick GU Base Pair Located in the Catalytic Core of the Antigenomic HDV Ribozyme
por: Lévesque, Dominique, et al.
Publicado: (2012)

A Conserved Target Site in HIV-1 Gag RNA is Accessible to Inhibition by Both an HDV Ribozyme and a Short Hairpin RNA
por: Scarborough, Robert J, et al.
Publicado: (2014)

The poly(A) site sequence in HDV RNA alters both extent and rate of self-cleavage of the antigenomic ribozyme
por: Brown, Abigail L., et al.
Publicado: (2008)

The genomic HDV ribozyme utilizes a previously unnoticed U-turn motif to accomplish fast site-specific catalysis
por: Sefcikova, Jana, et al.
Publicado: (2007)

Performance of Hepatitis Delta Virus (HDV) RNA Testing for the Diagnosis of Active HDV Infection: Systematic Review and Meta-analysis
por: Chen, Sisi, et al.
Publicado: (2023)

Broad-spectrum activity of bulevirtide against clinical isolates of HDV and recombinant pan-genotypic combinations of HBV/HDV
por: Mateo, Roberto, et al.
Publicado: (2023)

Circulation of HDV Genotypes in Brazil: Identification of a Putative Novel HDV-8 Subgenotype
por: Mello, Francisco C. A., et al.
Publicado: (2023)

HDV-Like Viruses
por: Pérez-Vargas, Jimena, et al.
Publicado: (2021)

AAV-HDV: An Attractive Platform for the In Vivo Study of HDV Biology and the Mechanism of Disease Pathogenesis (†)
por: Maestro, Sheila, et al.
Publicado: (2021)

Combination of Novel Therapies for HDV
por: Elazar, Menashe, et al.
Publicado: (2022)

A Review of HDV Infection
por: Caviglia, Gian Paolo, et al.
Publicado: (2022)

Variable In Vivo Hepatitis D Virus (HDV) RNA Editing Rates According to the HDV Genotype
por: Dziri, Samira, et al.
Publicado: (2021)

Pr77 and L1TcRz: A dual system within the 5′-end of L1Tc retrotransposon, internal promoter and HDV-like ribozyme
por: Sánchez-Luque, Francisco, et al.
Publicado: (2012)

HDV infection rates in northern Vietnam
por: Binh, Mai Thanh, et al.
Publicado: (2018)

HBV and HDV: New Treatments on the Horizon
por: Zuccaro, Valentina, et al.
Publicado: (2021)

HDV Pathogenesis: Unravelling Ariadne’s Thread
por: Tseligka, Eirini D., et al.
Publicado: (2021)

Chances for cure in chronic HBV/HDV coinfection
por: Iliescu, Gabriela, et al.
Publicado: (2014)

Hepatitis Delta Virus: HDV-HBV Interactions
por: Sureau, Camille
Publicado: (2006)

Constraint of Base Pairing on HDV Genome Evolution
por: Nagata, Saki, et al.
Publicado: (2021)

Both interferon alpha and lambda can reduce all intrahepatic HDV infection markers in HBV/HDV infected humanized mice
por: Giersch, Katja, et al.
Publicado: (2017)

Zinc protoporphyrin binding to telomerase complexes and inhibition of telomerase activity
por: Zhu, Zhaowen, et al.
Publicado: (2021)

Anti-HDV IgM as a Marker of Disease Activity in Hepatitis Delta
por: Wranke, Anika, et al.
Publicado: (2014)

Farnesoid X receptor alpha ligands inhibit HDV in vitro replication and virion infectivity
por: Legrand, Anne-Flore, et al.
Publicado: (2023)

Effects of flanking regions on HDV cotranscriptional folding kinetics
por: Wang, Yanli, et al.
Publicado: (2018)

In Vivo Models of HDV Infection: Is Humanizing NTCP Enough?
por: Giersch, Katja, et al.
Publicado: (2021)

Effective Inhibition of Human Immunodeficiency Virus 1 Replication by Engineered RNase P Ribozyme
por: Zeng, Wenbo, et al.
Publicado: (2012)

The unforeseeable hammerhead ribozyme
por: Hammann, Christian, et al.
Publicado: (2009)

Learning from ribozymes
por: Herschlag, Dan
Publicado: (2015)

Anti-HDV seroprevalance among patients with previous HBV infection
por: Sahin, Abdurrahman, et al.
Publicado: (2018)

Insight into the Contribution and Disruption of Host Processes during HDV Replication
por: Goodrum, Gabrielle, et al.
Publicado: (2018)

Management of Delta Hepatitis 45 Years after the Discovery of HDV
por: Brillanti, Stefano
Publicado: (2022)

Engineered RNase P Ribozymes Effectively Inhibit the Infection of Murine Cytomegalovirus in Animals
por: Li, Wei, et al.
Publicado: (2018)

Arginine Cofactors on the Polymerase Ribozyme
por: Yao, Chengguo, et al.
Publicado: (2011)

A combinatorial method to isolate short ribozymes from complex ribozyme libraries
por: Arriola, Joshua T, et al.
Publicado: (2020)

A GTP-synthesizing ribozyme selected by metabolic coupling to an RNA polymerase ribozyme
por: Akoopie, Arvin, et al.
Publicado: (2021)

A Faster Triphosphorylation Ribozyme
por: Dolan, Gregory F., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_69hf42e9h9id7jbf3agfvv4p37