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Inhibition of telomerase activity by HDV ribozyme in cancers

BACKGROUND: Telomerase plays an important role in cell proliferation and carcinogenesis and is believed to be a good target for anti-cancer drugs. Elimination of template function of telomerase RNA may repress the telomerase activity. METHODS: A pseudo-knotted HDV ribozyme (g.RZ57) directed against...

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Detalles Bibliográficos
Autores principales:	Lu, Yingying, Gu, Junchao, Jin, Dachuan, Gao, Yanjing, Yuan, Mengbiao
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024244/ https://www.ncbi.nlm.nih.gov/pubmed/21208462 http://dx.doi.org/10.1186/1756-9966-30-1

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