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Theoretical Analysis of the Stress Induced B-Z Transition in Superhelical DNA
We present a method to calculate the propensities of regions within a DNA molecule to transition from B-form to Z-form under negative superhelical stresses. We use statistical mechanics to analyze the competition that occurs among all susceptible Z-forming regions at thermodynamic equilibrium in a s...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024258/ https://www.ncbi.nlm.nih.gov/pubmed/21283778 http://dx.doi.org/10.1371/journal.pcbi.1001051 |