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Theoretical Analysis of the Stress Induced B-Z Transition in Superhelical DNA

We present a method to calculate the propensities of regions within a DNA molecule to transition from B-form to Z-form under negative superhelical stresses. We use statistical mechanics to analyze the competition that occurs among all susceptible Z-forming regions at thermodynamic equilibrium in a s...

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Detalles Bibliográficos
Autores principales:	Zhabinskaya, Dina, Benham, Craig J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024258/ https://www.ncbi.nlm.nih.gov/pubmed/21283778 http://dx.doi.org/10.1371/journal.pcbi.1001051

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