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Hepatic accumulation of intestinal cholesterol is decreased and fecal cholesterol excretion is increased in mice fed a high-fat diet supplemented with milk phospholipids

BACKGROUND: Milk phospholipids (PLs) reduce liver lipid levels when given as a dietary supplement to mice fed a high-fat diet. We have speculated that this might be due to reduced intestinal cholesterol uptake. METHODS: Mice were given a high-fat diet for 3 or 5 weeks that had no added PL or that we...

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Detalles Bibliográficos
Autores principales: Kamili, Alvin, Wat, Elaine, Chung, Rosanna WS, Tandy, Sally, Weir, Jacquelyn M, Meikle, Peter J, Cohn, Jeffrey S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024280/
https://www.ncbi.nlm.nih.gov/pubmed/21194424
http://dx.doi.org/10.1186/1743-7075-7-90