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Profiling spermatogenic failure in adult testes bearing Sox9-deficient Sertoli cells identifies genes involved in feminization, inflammation and stress
BACKGROUND: Sox9 (Sry box containing gene 9) is a DNA-binding transcription factor involved in chondrocyte development and sex determination. The protein's absence in testicular Sertoli nurse cells has been shown to disrupt testicular function in adults but little is known at the genome-wide le...
Autores principales: | Lardenois, Aurélie, Chalmel, Frédéric, Barrionuevo, Francisco, Demougin, Philippe, Scherer, Gerd, Primig, Michael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024295/ https://www.ncbi.nlm.nih.gov/pubmed/21182756 http://dx.doi.org/10.1186/1477-7827-8-154 |
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