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Risk of Acute Complications of Diabetes Among People With Schizophrenia in Ontario, Canada

OBJECTIVE: Diabetes mellitus (DM) is a complex, chronic disease requiring active self-management and coordinated care. This study aimed to evaluate the relationship between schizophrenia and risk of preventable, acute DM complications. RESEARCH DESIGN AND METHODS: With the use of administrative data...

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Detalles Bibliográficos
Autores principales: Becker, Taryn, Hux, Janet
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024356/
https://www.ncbi.nlm.nih.gov/pubmed/20978096
http://dx.doi.org/10.2337/dc10-1139
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author Becker, Taryn
Hux, Janet
author_facet Becker, Taryn
Hux, Janet
author_sort Becker, Taryn
collection PubMed
description OBJECTIVE: Diabetes mellitus (DM) is a complex, chronic disease requiring active self-management and coordinated care. This study aimed to evaluate the relationship between schizophrenia and risk of preventable, acute DM complications. RESEARCH DESIGN AND METHODS: With the use of administrative data, a retrospective study assessed acute DM complications (emergency department [ED] visits or hospitalization for hypo- or hyperglycemia and hospital admissions for infections) among Ontario residents ages 18–50 with schizophrenia and newly diagnosed DM between 1995 and 2005, comparing people with and without pre-existing schizophrenia. Primary outcome was ED visit or hospitalization for hypo- or hyperglycemia. Secondary outcome was the first of either the primary outcome or hospitalization for infection. RESULTS: People with schizophrenia had a 74% greater risk of requiring a hospital visit for hypo- or hyperglycemia (hazard ratio [HR] = 1.74, 95% confidence interval 1.42–2.12) compared with those without schizophrenia. The risk was similar when the outcome included infection (HR = 1.62, 95% CI 1.39–1.89). Outcomes remained significant after adjustment for baseline characteristics. CONCLUSIONS: People with schizophrenia are at greater risk for developing an acute complication of DM. Understanding this relationship will direct future studies assessing barriers to care and implementation of individualized approaches to care for this population.
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spelling pubmed-30243562012-02-01 Risk of Acute Complications of Diabetes Among People With Schizophrenia in Ontario, Canada Becker, Taryn Hux, Janet Diabetes Care Original Research OBJECTIVE: Diabetes mellitus (DM) is a complex, chronic disease requiring active self-management and coordinated care. This study aimed to evaluate the relationship between schizophrenia and risk of preventable, acute DM complications. RESEARCH DESIGN AND METHODS: With the use of administrative data, a retrospective study assessed acute DM complications (emergency department [ED] visits or hospitalization for hypo- or hyperglycemia and hospital admissions for infections) among Ontario residents ages 18–50 with schizophrenia and newly diagnosed DM between 1995 and 2005, comparing people with and without pre-existing schizophrenia. Primary outcome was ED visit or hospitalization for hypo- or hyperglycemia. Secondary outcome was the first of either the primary outcome or hospitalization for infection. RESULTS: People with schizophrenia had a 74% greater risk of requiring a hospital visit for hypo- or hyperglycemia (hazard ratio [HR] = 1.74, 95% confidence interval 1.42–2.12) compared with those without schizophrenia. The risk was similar when the outcome included infection (HR = 1.62, 95% CI 1.39–1.89). Outcomes remained significant after adjustment for baseline characteristics. CONCLUSIONS: People with schizophrenia are at greater risk for developing an acute complication of DM. Understanding this relationship will direct future studies assessing barriers to care and implementation of individualized approaches to care for this population. American Diabetes Association 2011-02 2011-01-20 /pmc/articles/PMC3024356/ /pubmed/20978096 http://dx.doi.org/10.2337/dc10-1139 Text en © 2011 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.
spellingShingle Original Research
Becker, Taryn
Hux, Janet
Risk of Acute Complications of Diabetes Among People With Schizophrenia in Ontario, Canada
title Risk of Acute Complications of Diabetes Among People With Schizophrenia in Ontario, Canada
title_full Risk of Acute Complications of Diabetes Among People With Schizophrenia in Ontario, Canada
title_fullStr Risk of Acute Complications of Diabetes Among People With Schizophrenia in Ontario, Canada
title_full_unstemmed Risk of Acute Complications of Diabetes Among People With Schizophrenia in Ontario, Canada
title_short Risk of Acute Complications of Diabetes Among People With Schizophrenia in Ontario, Canada
title_sort risk of acute complications of diabetes among people with schizophrenia in ontario, canada
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024356/
https://www.ncbi.nlm.nih.gov/pubmed/20978096
http://dx.doi.org/10.2337/dc10-1139
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