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Liver ATP Synthesis Is Lower and Relates to Insulin Sensitivity in Patients With Type 2 Diabetes

OBJECTIVE: Steatosis associates with insulin resistance and may even predict type 2 diabetes and cardiovascular complications. Because muscular insulin resistance relates to myocellular fat deposition and disturbed energy metabolism, we hypothesized that reduced hepatic ATP turnover (fATP) underlies...

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Detalles Bibliográficos
Autores principales: Schmid, Albrecht Ingo, Szendroedi, Julia, Chmelik, Marek, Krššák, Martin, Moser, Ewald, Roden, Michael
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024365/
https://www.ncbi.nlm.nih.gov/pubmed/21216854
http://dx.doi.org/10.2337/dc10-1076