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The Microbe-Derived Short Chain Fatty Acid Butyrate Targets miRNA-Dependent p21 Gene Expression in Human Colon Cancer
Colonic microbiota ferment non-absorbed dietary fiber to produce prodigious amounts of short chain fatty acids (SCFAs) that benefit the host through a myriad of metabolic, trophic, and chemopreventative effects. The chemopreventative effects of the SCFA butyrate are, in part, mediated through induct...
Autores principales: | Hu, Shien, Dong, Tien Sy, Dalal, Sushila R., Wu, Feng, Bissonnette, Marc, Kwon, John H., Chang, Eugene B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024403/ https://www.ncbi.nlm.nih.gov/pubmed/21283757 http://dx.doi.org/10.1371/journal.pone.0016221 |
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