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Animal Models of Cardiac Disease and Stem Cell Therapy

Animal models that mimic cardiovascular diseases are indispensable tools for understanding the mechanisms underlying the diseases at the cellular and molecular level. This review focuses on various methods in preclinical research to create small animal models of cardiac diseases, such as myocardial...

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Detalles Bibliográficos
Autores principales: Ou, Lailiang, Li, Wenzhong, Liu, Yi, Zhang, Yue, Jie, Shen, Kong, Deling, Steinhoff, Gustav, Ma, Nan
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024564/
https://www.ncbi.nlm.nih.gov/pubmed/21258568
http://dx.doi.org/10.2174/1874192401004010231
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author Ou, Lailiang
Li, Wenzhong
Liu, Yi
Zhang, Yue
Jie, Shen
Kong, Deling
Steinhoff, Gustav
Ma, Nan
author_facet Ou, Lailiang
Li, Wenzhong
Liu, Yi
Zhang, Yue
Jie, Shen
Kong, Deling
Steinhoff, Gustav
Ma, Nan
author_sort Ou, Lailiang
collection PubMed
description Animal models that mimic cardiovascular diseases are indispensable tools for understanding the mechanisms underlying the diseases at the cellular and molecular level. This review focuses on various methods in preclinical research to create small animal models of cardiac diseases, such as myocardial infarction, dilated cardiomyopathy, heart failure, myocarditis and cardiac hypertrophy, and the related stem cell treatment for these diseases.
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spelling pubmed-30245642011-01-21 Animal Models of Cardiac Disease and Stem Cell Therapy Ou, Lailiang Li, Wenzhong Liu, Yi Zhang, Yue Jie, Shen Kong, Deling Steinhoff, Gustav Ma, Nan Open Cardiovasc Med J Article Animal models that mimic cardiovascular diseases are indispensable tools for understanding the mechanisms underlying the diseases at the cellular and molecular level. This review focuses on various methods in preclinical research to create small animal models of cardiac diseases, such as myocardial infarction, dilated cardiomyopathy, heart failure, myocarditis and cardiac hypertrophy, and the related stem cell treatment for these diseases. Bentham Open 2010-11-26 /pmc/articles/PMC3024564/ /pubmed/21258568 http://dx.doi.org/10.2174/1874192401004010231 Text en © Ou et al.; Licensee Bentham Open. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Ou, Lailiang
Li, Wenzhong
Liu, Yi
Zhang, Yue
Jie, Shen
Kong, Deling
Steinhoff, Gustav
Ma, Nan
Animal Models of Cardiac Disease and Stem Cell Therapy
title Animal Models of Cardiac Disease and Stem Cell Therapy
title_full Animal Models of Cardiac Disease and Stem Cell Therapy
title_fullStr Animal Models of Cardiac Disease and Stem Cell Therapy
title_full_unstemmed Animal Models of Cardiac Disease and Stem Cell Therapy
title_short Animal Models of Cardiac Disease and Stem Cell Therapy
title_sort animal models of cardiac disease and stem cell therapy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024564/
https://www.ncbi.nlm.nih.gov/pubmed/21258568
http://dx.doi.org/10.2174/1874192401004010231
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