Genetic risk profiling for prediction of type 2 diabetes

Type 2 diabetes (T2D) is a common disease caused by a complex interplay between many genetic and environmental factors. Candidate gene studies and recent collaborative genome-wide association efforts revealed at least 38 common single nucleotide polymorphisms (SNPs) associated with increased risk of...

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Detalles Bibliográficos
Autores principales: Mihaescu, Raluca, Meigs, James, Sijbrands, Eric, Janssens, A. Cecile
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Evidence on Genomic Tests
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024707/
https://www.ncbi.nlm.nih.gov/pubmed/21278902
http://dx.doi.org/10.1371/currents.RRN1208
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author Mihaescu, Raluca
Meigs, James
Sijbrands, Eric
Janssens, A. Cecile
author_facet Mihaescu, Raluca
Meigs, James
Sijbrands, Eric
Janssens, A. Cecile
author_sort Mihaescu, Raluca
collection PubMed
description Type 2 diabetes (T2D) is a common disease caused by a complex interplay between many genetic and environmental factors. Candidate gene studies and recent collaborative genome-wide association efforts revealed at least 38 common single nucleotide polymorphisms (SNPs) associated with increased risk of T2D. Genetic testing of multiple SNPs is considered a potentially useful tool for early detection of individuals at high diabetes risk leading to improved targeting of preventive interventions.
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spelling pubmed-30247072011-01-28 Genetic risk profiling for prediction of type 2 diabetes Mihaescu, Raluca Meigs, James Sijbrands, Eric Janssens, A. Cecile PLoS Curr Evidence on Genomic Tests Type 2 diabetes (T2D) is a common disease caused by a complex interplay between many genetic and environmental factors. Candidate gene studies and recent collaborative genome-wide association efforts revealed at least 38 common single nucleotide polymorphisms (SNPs) associated with increased risk of T2D. Genetic testing of multiple SNPs is considered a potentially useful tool for early detection of individuals at high diabetes risk leading to improved targeting of preventive interventions. Public Library of Science 2011-01-11 /pmc/articles/PMC3024707/ /pubmed/21278902 http://dx.doi.org/10.1371/currents.RRN1208 Text en http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Evidence on Genomic Tests
Mihaescu, Raluca
Meigs, James
Sijbrands, Eric
Janssens, A. Cecile
Genetic risk profiling for prediction of type 2 diabetes
title Genetic risk profiling for prediction of type 2 diabetes
title_full Genetic risk profiling for prediction of type 2 diabetes
title_fullStr Genetic risk profiling for prediction of type 2 diabetes
title_full_unstemmed Genetic risk profiling for prediction of type 2 diabetes
title_short Genetic risk profiling for prediction of type 2 diabetes
title_sort genetic risk profiling for prediction of type 2 diabetes
topic Evidence on Genomic Tests
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024707/
https://www.ncbi.nlm.nih.gov/pubmed/21278902
http://dx.doi.org/10.1371/currents.RRN1208
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AT janssensacecile geneticriskprofilingforpredictionoftype2diabetes

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