TF-centered downstream gene set enrichment analysis: Inference of causal regulators by integrating TF-DNA interactions and protein post-translational modifications information

BACKGROUND: Inference of causal regulators responsible for gene expression changes under different conditions is of great importance but remains rather challenging. To date, most approaches use direct binding targets of transcription factors (TFs) to associate TFs with expression profiles. However,...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Tan, Yejun, Huang, Tao, Ding, Guohui, Tu, Zhidong, Liu, Lei, Li, Yixue, Dai, Hongyue, Xie, Lu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024863/
https://www.ncbi.nlm.nih.gov/pubmed/21172055
http://dx.doi.org/10.1186/1471-2105-11-S11-S5

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